J. L. Gomez-Skarmeta

The paper constructs a single-cell RNA-seq atlas of amphioxus neurula stage to investigate the evolutionary origins of vertebrate head mesoderm.

This study identifies a biphasic developmental program in hemichordates, revealing conserved gene regulatory networks and cis-regulatory elements across deuterostomes.

This study identifies genomic rearrangements and regulatory changes in the little skate that contribute to the evolution of wing-like fin appendages.

This study compares small-scale gene duplication patterns between amphioxus and vertebrates, finding similar duplication histories and functional constraints despite amphioxus' slower evolution.

This study shows that the Shh/Gli3 gene regulatory network controls proliferation in distal fin and limb regions, revealing deep homology between these structures.

The paper shows that increased interconnectivity between signaling pathways and gene regulatory networks contributed to vertebrate evolution by enabling new gene expression patterns and cell types.

The paper profiles epigenomic features in primate LCLs to reveal evolutionary patterns of epigenetic activity in gene regulation.

The paper shows that ancient genomic regulatory blocks (GRBs) were maintained as single copies in humans after vertebrate whole genome duplications, with their duplicated copies dismantled to form gene deserts.

The paper investigates why different genes underlie the evolution of similar traits in Drosophila by comparing gene regulatory networks in larval and leg trichome development.