Cohesin promotes stochastic domain intermingling to ensure proper regulation of boundary-proximal genes
J. Luppino, D. Park, S. Nguyen, Y. Lan, Z. Xu, E. Joyce
This study quantifies inter-TAD interactions in human cells and shows cohesin depletion reduces both intra- and inter-domain interactions, affecting gene expression near boundaries.
bioRxiv · Jul 10, 2019Cell Biology