Stepwise C-Terminal Truncation of Cardiac Troponin T Alters Function at Low and Saturating Ca2+
D. Johnson, C. W. Angus, J. M. Chalovich
This study shows that truncating the C-terminal 14 amino acids of cardiac troponin T alters its function at both low and saturating Ca2+ levels by affecting the inactive B state and active M state.
bioRxiv · Apr 19, 2018Biochemistry