Respiratory tract Moraxella catarrhalis and Klebsiella pneumoniae can promote pathogenicity of myelin-reactive Th17 cells
J. M. Mannion, B. M. Segal, R. M. McLoughlin, S. J. Lalor
This study shows that respiratory bacteria Moraxella catarrhalis and Klebsiella pneumoniae enhance the pathogenicity of myelin-reactive Th17 cells, leading to increased GM-CSF and GM-CSF+IFNγ production and worsened EAE.
bioRxiv · Mar 30, 2023 · PreprintImmunology