Author

J. M. Ostrem

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Biophysics· 1

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Tutter· 1 shared B. K. Hua· 1 shared B. Tong· 1 shared F. Berst· 1 shared F. J. Zecri· 1 shared J. W. Mason· 1 shared K. Briner· 1 shared S. A. Tang· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

A. Tutter

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1 paper

Recent·Most cited

Rational screening for cooperativity in small-molecule inducers of protein-protein associations

S. Liu, B. Tong, J. W. Mason, J. M. Ostrem, A. Tutter, B. K. Hua, S. A. Tang, S. Bonazzi, K. Briner, F. Berst, F. J. Zecri, S. L. Schreiber

The paper introduces a binding-based screen to identify cooperative small-molecule inducers of protein-protein interactions, identifying a compound with high cooperativity comparable to classical molecular glues.

bioRxiv · May 22, 2023Biophysics