Author

J. M. Ribes

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

B. Mistry· 1 shared D. Sangar· 1 shared E. Hill· 1 shared G. S. Jackson· 1 shared J. Bieschke· 1 shared K. Jack· 1 shared M. Batchelor· 1 shared S. Mead· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

B. Mistry

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1 paper

Recent·Most cited

Syntaxin 6 delays prion protein fibril formation and prolongs presence of toxic aggregation intermediates

D. Sangar, E. Hill, K. Jack, M. Batchelor, B. Mistry, J. M. Ribes, G. S. Jackson, S. Mead, J. Bieschke

This study shows syntaxin-6 inhibits PrP fibril formation but prolongs toxic intermediate aggregates, suggesting it acts as an anti-chaperone in prion disease.

bioRxiv · Aug 25, 2022Biochemistry