Author

J. Miratsky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Singharoy· 2 shared J. Vant· 2 shared A. Shukla· 1 shared D. Tan· 1 shared E. Nudler· 1 shared G. L. Lee· 1 shared J. K. Cava· 1 shared K. Dryden· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

A. Singharoy

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2 papers

Recent·Most cited

Structural mechanism of HP1-dependent transcriptional repression and chromatin compaction

V. Sokolova, J. Miratsky, V. Svetlov, M. Brenowitz, J. Vant, T. S. Lewis, K. Dryden, G. L. Lee, S. L. Sarkar, E. Nudler, A. Singharoy, D. Tan

This study determines the cryo-EM structure of HP1 bound to an H2A.Z nucleosome, revealing two binding sites and their roles in transcriptional repression and chromatin compaction.

bioRxiv · Nov 30, 2023Biochemistry

Learning Free Energy Pathways through Reinforcement Learning of Adaptive Steered Molecular Dynamics

N. Ho, J. K. Cava, J. Vant, A. Shukla, J. Miratsky, P. Turaga, R. Maciejewski, A. Singharoy

This paper develops a reinforcement learning framework to compute low free energy pathways between states using adaptive steered molecular dynamics and robotics planning.

bioRxiv · Oct 4, 2022 · PreprintBiophysics