Dynamic regulation of translation quality control associated with ribosome stalling
D. H. Goldman, N. M. Livingston, J. Movsik, B. Wu, R. Green
The paper develops a SunTag-based reporter to study ribosome stalling during translation of poly(A)-containing mRNAs and finds that stalled ribosomes are slowly cleared by quality control machinery, targeting nascent proteins rather than mRNA.
bioRxiv · May 29, 2020 · PreprintBiochemistry