Dual protease type XIII/pepsin digestion offers superior resolution and overlap for the analysis of histone tails by HX-MS
J. Mullahoo, T. Zhang, K. Clauser, S. A. Carr, J. D. Jaffe, M. Papanastasiou
This study demonstrates that dual protease type XIII/pepsin digestion improves HX-MS analysis of histone tails by providing better resolution and peptide overlap.
bioRxiv · Oct 1, 2019Biochemistry