Author

J. N. Cash

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Research Focus:software / tool· 1 Assay:structural biology· 1

Frequent Co-Authors

M. A. Cianfrocco· 3 shared J. J. G. Tesmer· 2 shared C.-L. Chen· 1 shared J. S. Gutkind· 1 shared S. K. Ravala· 1 shared S. Kearns· 1 shared S. Li· 1 shared S. R. Adame-Garcia· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersBiophysics

M. A. Cianfrocco

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Author profile →

3 papers

Recent·Most cited

Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4

S. K. Ravala, S. R. Adame-Garcia, S. Li, C.-L. Chen, M. A. Cianfrocco, J. S. Gutkind, J. N. Cash, J. J. G. Tesmer

This study identifies structural changes in P-Rex1 upon activation by PIP3 and inhibition by IP4, revealing how these interactions regulate its GEF activity.

bioRxiv · Sep 15, 2023Biochemistry

High-resolution cryo-EM using beam-image shift at 200 keV

J. N. Cash, S. Kearns, Y. A. Li, M. A. Cianfrocco

The paper tests beam-image shift data collection at 200 keV cryo-EM on aldolase, showing resolution improvement from 4.9 to 2.8 Å through aberration correction.

IUCrJ · Oct 29, 2020Peer-reviewedBiophysics

High-throughput cryo-EM enabled by user-free preprocessing routines

Y. Li, J. N. Cash, J. J. G. Tesmer, M. A. Cianfrocco

This paper introduces an automatic cryo-EM preprocessing pipeline using deep learning and image analysis tools, verified on multiple datasets and extended to include user-free sample screening.

bioRxiv · Dec 20, 2019Biophysics