Initial spindle positioning at the oocyte center protects against incorrect kinetochore-microtubule attachment and aneuploidy in mice
J. N. Kincade, A. Hlavacek, T. Akera, A. Z. Balboula
This study shows that initial central spindle positioning in mouse oocytes prevents incorrect kinetochore-microtubule attachment and aneuploidy by avoiding premature cortical CDC42 signaling.
bioRxiv · Jun 28, 2020Cell Biology