Oxidative Stress Induced Senescence Gives Rise to Transcriptionally Distinct Physiological States
N. Burnaevskiy, J. Oshima, A. R. Mendenhall
The paper uses single-cell RNA-sequencing to identify two distinct transcriptional states in oxidative stress-induced senescent cells and suggests combination senolytic drugs may be needed.
bioRxiv · May 18, 2022 · PreprintCell Biology