Author

J. P. Bollback

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

M. Lagator· 2 shared C. C. Guet· 1 shared C. M. Lewis· 1 shared D. Toledo-Aparicio· 1 shared G. Tkacik· 1 shared H. A. Kirit· 1 shared H. Acar Kirit· 1 shared K. Sankaranarayanan· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersEvolutionary Biology

M. Lagator

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Author profile →

4 papers

Recent·Most cited

Evolutionary barriers to horizontal gene transfer in macrophage associated Salmonella.

R. P. Bhatia, H. A. Kirit, C. M. Lewis, K. Sankaranarayanan, J. P. Bollback

This study measures the fitness effects of horizontally transferred genes from E. coli to Salmonella in infection environments, finding gene length and environmental factors significantly hinder HGT.

bioRxiv · Apr 1, 2022Microbiology

Structure and Evolution of Constitutive Bacterial Promoters

M. Lagator, S. Sarikas, M. Steinrück, D. Toledo-Aparicio, J. P. Bollback, G. Tkacik, C. C. Guet

The paper develops a biophysical model to predict constitutive gene expression from bacterial promoter sequences and estimates the prevalence of functional promoters in random sequences.

bioRxiv · May 19, 2020 · PreprintEvolutionary Biology

Experimental Determination of Evolutionary Barriers to Horizontal Gene Transfer

H. Acar Kirit, M. Lagator, J. P. Bollback

The paper experimentally measures fitness effects of horizontal gene transfer between Salmonella and E. coli, finding that dosage sensitivity, gene length, and protein disorder are key barriers, not previously identified gene function or interaction counts.

bioRxiv · Aug 2, 2019Microbiology

CRISPR-based Herd Immunity Limits Phage Epidemics in Bacterial Populations

P. Payne, L. Geyrhofer, N. H. Barton, J. P. Bollback

The paper studies herd immunity in bacterial populations using CRISPR-resistant and susceptible E. coli and T7 phages, finding that spatial structure, growth rate, and phage replication rate influence epidemic dynamics.

bioRxiv · Aug 28, 2017Microbiology