Loss of Bardet-Biedl syndrome proteins causes synaptic aberrations in principal neurons
N. Haq, C. Schmidt-Hieber, F. J. Sialana, L. Ciani, J. P. Heller, M. Stewart, L. Bentley, S. Wells, R. J. Rodenburg, P. M. Nolan, E. Forsythe, M. C. Wu, G. Lubec, M. Hausser, P. Beales, S. Christou-Savina
This study shows that loss of Bardet-Biedl syndrome proteins causes synaptic dysfunction in principal neurons, contributing to cognitive impairment in BBS patients.
bioRxiv · Mar 18, 2019Cell Biology