Downregulation of ribosomal RNA (rRNA) genes in human head and neck squamous cell carcinoma (HNSCC) cells is linked to rDNA promoter hypermethylation
N. Priyadarshini, N. V. Puppala, J. P. Jayaprakash, P. Khandelia, V. Sharma, G. Mohannath
The paper shows that rRNA genes are downregulated and hypermethylated in HNSCC cell lines, suggesting a potential role in cancer prognosis and diagnosis.
bioRxiv · Mar 13, 2023 · PreprintCancer Biology