Author

J. P. Reddington

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Evolutionary Biology· 2

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Organism:Drosophila· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

C. Girardot· 2 shared P. Khoueiry· 2 shared D. A. Garfield· 1 shared E. E. M. Furlong· 1 shared E. Furlong· 1 shared J. Liu· 1 shared M. Robinson-Rechavi· 1 shared P.-C. Peng· 1 shared

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2018-2020 · peak 1/yr

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10 top collaborators · 29 mutual co-author links

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2 shared papersEvolutionary Biology

C. Girardot

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2 papers

Recent·Most cited

The hourglass model of evolutionary conservation during embryogenesis extends to developmental enhancers with signatures of positive selection

J. Liu, R. R. Viales, P. Khoueiry, J. P. Reddington, C. Girardot, E. Furlong, M. Robinson-Rechavi

The paper identifies a higher proportion of conserved enhancers during the phylotypic period of Drosophila embryogenesis and detects positive selection on enhancers at early and late stages.

bioRxiv · Nov 2, 2020Evolutionary Biology

The role of chromatin accessibility in cis-regulatory evolution

P.-C. Peng, P. Khoueiry, C. Girardot, J. P. Reddington, D. A. Garfield, E. E. M. Furlong, S. Sinha

This study examines how chromatin accessibility and sequence changes influence the evolutionary divergence of transcription factor binding in Drosophila species.

bioRxiv · Oct 15, 2018Evolutionary Biology