Author

J. P. Thaler

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Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Niraula· 1 shared J. M. Frey· 1 shared K. M. Ness· 1 shared M. D. Dorfman· 1 shared R. D. Fasnacht· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperPhysiology

A. Niraula

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1 paper

Recent·Most cited

Prostaglandin PGE2 receptor EP4 regulates microglial phagocytosis and increases susceptibility to diet-induced obesity

A. Niraula, R. D. Fasnacht, K. M. Ness, J. M. Frey, M. D. Dorfman, J. P. Thaler

This study shows that microglial EP4 receptor deletion reduces diet-induced obesity and improves insulin sensitivity by decreasing microglial phagocytosis and altering POMC neuron interactions.

Diabetes · Nov 1, 2022Peer-reviewedPhysiology