Clustering and reverse transcription of HIV-1 genomes in nuclear niches of macrophages
E. Rensen, F. Mueller, V. Scoca, J. Parmar, P. Souque, C. Zimmer, F. Di Nunzio
This study shows HIV-1 RNA clusters in macrophage nuclei, where reverse transcription and DNA formation occur, challenging the view that these processes are spatially and temporally separated.
bioRxiv · Apr 12, 2020Microbiology