Author

J. R. Eles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:imaging· 2 Research Focus:synaptic & neural circuits· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:electrophysiology· 1

Frequent Co-Authors

T. D. Y. Kozai· 3 shared S. M. Wellman· 2 shared F. Li· 1 shared H. Sohal· 1 shared I. N. McNamara· 1 shared K. A. Ludwig· 1 shared K. C. Steiger· 1 shared K. C. Stieger· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersBioengineering

T. D. Y. Kozai

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3 papers

Recent·Most cited

Electrode sharpness and insertion speed reduce tissue damage near high-density penetrating arrays

I. N. McNamara, S. M. Wellman, L. Li, J. R. Eles, S. Savya, H. Sohal, M. Angle, T. D. Y. Kozai

This study evaluates how electrode sharpness and insertion speed affect tissue damage when implanting high-density neural arrays in mice and rats, finding that electro-sharpened arrays and faster insertion reduce cellular damage and BBB compromise.

bioRxiv · Nov 22, 2023 · PreprintBioengineering

In vivo spatiotemporal dynamics of astrocyte reactivity following neural electrode implantation

S. P. Savya, F. Li, S. Lam, S. M. Wellman, K. C. Stieger, K. Chen, J. R. Eles, T. D. Y. Kozai

This study uses two-photon microscopy to observe astrocyte reactivity in mouse brains after intracortical microelectrode implantation, revealing distinct spatiotemporal dynamics compared to other glial cells.

bioRxiv · Jul 1, 2022Bioengineering

In vivo microstimulation with cathodic and anodic asymmetric waveforms modulates spatio-temporal calcium dynamics in cortical neuropil and pyramidal neurons of male mice.

K. C. Steiger, J. R. Eles, K. A. Ludwig, T. D. Y. Kozai

This study shows that asymmetric electrical stimulation waveforms modulate neuronal activation patterns in mice, with cathodic asymmetry reducing spatial spread and anodic asymmetry increasing it.

bioRxiv · Dec 16, 2019Bioengineering