Transcription factors ERα and Sox2 have differing multiphasic DNA and RNA binding mechanisms
W. O. Hemphill, H. R. Steiner, J. R. Kominsky, D. S. Wuttke, T. R. Cech
This study investigates the DNA and RNA binding kinetics of ERα and Sox2, revealing distinct multiphasic binding mechanisms with ER showing novel triphasic association behavior.
bioRxiv · Mar 18, 2024Biophysics