D. S. Wuttke

Transcription factors ERα and Sox2 have differing multiphasic DNA and RNA binding mechanisms

This study investigates the DNA and RNA binding kinetics of ERα and Sox2, revealing distinct multiphasic binding mechanisms with ER showing novel triphasic association behavior.

The RNA-binding domain of hnRNP U extends beyond the RGG/RG motifs

This study identifies and characterizes the extended RNA-binding domain of hnRNP U, revealing two RGG/RG elements that work redundantly to enhance RNA binding.

CST does not evict elongating telomerase but prevents initiation by ssDNA binding

The paper investigates CST's role in telomerase inhibition and shows it does not terminate ongoing telomerase extension but prevents initiation through ssDNA binding.

Cyp33 Binds AU-Rich RNA Motifs via an Extended Interface that Competitively Disrupts the Gene Repressive Cyp33-MLL1 Interaction in vitro

This study identifies an RNA binding motif for Cyp33 and shows RNA can disrupt its interaction with MLL1, affecting chromatin remodeling.

The cryo-EM structure of human CST reveals a two-megadalton decameric assembly bound to telomeric DNA

The paper reports the cryo-EM structure of human CST bound to telomeric DNA, revealing a decameric supercomplex and providing insights into CST function and disease associations.