Cancer BiologybioRxiv
RNA allelic frequencies of somatic mutations encode substantial functional information in cancers
J. R. M. Black, T. P. Jones, C. Martinez-Ruiz…·N. McGranahan
This study uses RNA variant allele frequencies to identify cancer genes with RVdriver, showing it can detect both known and novel cancer genes with performance comparable to DNA-based methods.
DOI 10.1186/s13059-025-03557-y