Evolutionary BiologybioRxiv
Genomic signatures of extensive inbreeding in Isle Royale wolves, a population on the threshold of extinction
J. A. Robinson, J. Räikkönen, L. M. Vucetich…·R. K. Wayne
The paper analyzes genomic data from Isle Royale wolves to assess the effects of inbreeding and finds that homozygosity of deleterious mutations, not heterozygosity or variant count, correlates with inbreeding depression.
DOI 10.1126/sciadv.aau0757