Ligand-induced motions in pentameric ligand-gated ion channels revealed by EPR spectroscopy
V. Tiwari, J. S. Borchardt, A. Schuh, C. S. Klug, C. Czajkowski
This study uses EPR spectroscopy to reveal ligand-induced structural changes in the extracellular domain of GLIC, showing inward motions associated with agonist-induced closed pre-activated states.
bioRxiv · Nov 4, 2020 · PreprintBiophysics