J. S. Dahlin

Single-cell transcriptomics reveals the identity and regulators of human mast cell progenitors

Single-cell analysis of human hematopoiesis uncovers the stage at which FcεRI appears during mast cell differentiation and reveals disparate effects of IL-3, IL-5 and IL-33 on mast cell progenitor proliferation, survival, and suppression of FcεRI expression.

Immunoprofiling reveals novel mast cell receptors and a continuous nature of human lung mast cell heterogeneity

The paper identifies 102 cell surface markers on human lung mast cells, showing continuous heterogeneity rather than distinct subpopulations.

Single-cell molecular profiling provides a high-resolution map of basophil and mast cell differentiation

This study maps basophil and mast cell differentiation using single-cell RNA sequencing and flow cytometry in mice, revealing distinct trajectories and lineage-specific gene regulation.

Single-cell analysis reveals the KIT D816V mutation in hematopoietic stem and progenitor cells in systemic mastocytosis

This study identifies the KIT D816V mutation in hematopoietic stem and progenitor cells in systemic mastocytosis, showing it is present in nearly all mast cells and spans the hematopoietic lineage.