Piezo1 mechanosensing regulates integrin-dependent chemotactic migration in human T cells
C. S. C. Liu, T. Mandal, P. Biswas, M. A. Hoque, P. Bandopadhyay, B. P. Sinha, J. Sarif, R. D'Rozario, D. K. Sinha, B. Sinha, D. Ganguly
This study shows that Piezo1 mechanosensing is essential for integrin-dependent chemotactic migration of human T cells by mediating calcium influx and calpain activation.
bioRxiv · Aug 16, 2022Immunology