Achieving dendritic cell subset-specific targeting in vivo by site-directed conjugation of targeting antibodies to nanocarriers
J. Simon, M. Fichter, G. Kuhn, M. Brueckner, C. Kappel, J. Schunke, S. Grabbe, K. Landfester, V. Mailaender
This paper develops a site-directed conjugation method to attach antibodies to nanocarriers for specific targeting of dendritic cell subsets in vivo, improving vaccine efficacy by avoiding non-specific uptake.
bioRxiv · Jul 14, 2021Bioengineering