Author

J. Seravalli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Batyuk· 1 shared A. E. Cohen· 1 shared A. Guha· 1 shared A. Lyubimov· 1 shared A. S. Brewster· 1 shared B. Hayes· 1 shared D. B. Berkowitz· 1 shared D. Budday· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

A. Batyuk

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2 papers

Recent·Most cited

Cobalt-sulfur coordination chemistry drives B12 loading onto methionine synthase

R. Mascarenhas, A. Guha, Z. Li, M. Ruetz, S. An, J. Seravalli, R. Banerjee

This study identifies how MMADHC uses Co-S coordination lability to transfer cobalamin to methionine synthase, explaining homocystinuria caused by MMADHC variants.

bioRxiv · Jul 25, 2023 · PreprintBiochemistry

Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis

M. DasGupta, D. Budday, S. H. P. de Oliveira, P. Madzelan, D. Marchany-Rivera, J. Seravalli, B. Hayes, R. G. Sierra, S. Boutet, M. Hunter, R. Alonso-Mori, A. Batyuk, J. Wierman, A. Lyubimov, A. S. Brewster, , M. A. Wilson

This study uses mix-and-inject XFEL crystallography to observe conformational changes in isocyanide hydratase during catalysis, showing how cysteine modification affects enzyme dynamics and function.

bioRxiv · Aug 24, 2019Biochemistry