Peptidome Surveillance Across Evolving SARS-CoV-2 Lineages Reveals HLA Binding Conservation in Nucleocapsid Among Variants With Most Potential for T-Cell Epitope Loss In Spike
K. Wnuk, J. Sudol, P. R. Spilman, P. Soon-Shiong
The paper analyzes HLA-I and HLA-II binding peptides in SARS-CoV-2 spike and nucleocapsid proteins across variants to assess T-cell epitope conservation and evasion potential.
bioRxiv · Mar 18, 2022Immunology