A comprehensive map of genetic interactions in childhood cancer reveals multiple underlying biological mechanisms
J. T. Daub, S. Amini, D. J. E. Kersjes, X. Ma, N. Jäger, J. Zang, S. M. Pfister, F. C. P. Holstege, P. Kemmeren
The paper identifies genetic interactions in childhood cancers using a statistical pipeline, revealing 15 co-occurring and 27 mutually exclusive gene pairs, with most mechanisms linked to tumor subtypes or pathways.
bioRxiv · Nov 17, 2020Cancer Biology