Early persistence of recipient stem-cells and T-cell dysregulation are associated with relapse after transplant in AML/MDS
Nurefsan E. Sariipek, Ksenia R. Safina, Wesley S. Lu, Shuqiang Li, J. Thomas Janes, McKayla Van Orden, Kenneth J. Livak, Haynes Heaton, Vincent T. Ho, John Koreth, Marlise Rachael Luskin, Gabriel Kenneth Griffin, Jacqueline Suen Garcia, Robert Coleman Lindsley, Corey S. Cutler, , Peter van Galen
The paper identifies recipient stem-cell persistence and T-cell dysregulation as predictors of relapse after HSCT in AML/MDS by analyzing single-cell RNA and TCR sequencing data.
bioRxiv · Nov 13, 2025 · PreprintCancer Biology