Differential Effector Response of Amnion- and Adipose-Derived Mesenchymal Stem Cells to Inflammation; Implications for Intradiscal Therapy
R. Borem, A. Madeline, M. Bowman, S. Gill, J. Tokish, J. Mercuri
This study compares the inflammatory response of amnion- and adipose-derived mesenchymal stem cells in intervertebral disc degeneration, finding AM-MSCs produce more anti-inflammatory cytokines and chondrogenic matrix while AD-MSCs proliferate more and produce pro-inflammatory cytokines.
bioRxiv · Jan 17, 2019Bioengineering