Author

R. Borem

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Organism:human· 1

Frequent Co-Authors

A. Madeline· 4 shared J. Mercuri· 4 shared S. Gill· 4 shared J. Easley· 2 shared J. Walters· 2 shared L. Madeline· 2 shared J. Tokish· 1 shared M. Bowman· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 25 mutual co-author links

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4 shared papersBioengineering

A. Madeline

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4 papers

Recent·Most cited

Characterization of chondroitinase-induced lumbar intervertebral disc degeneration in a sheep model intended for assessing biomaterials

R. Borem, J. Walters, A. Madeline, L. Madeline, S. Gill, J. Easley, J. Mercuri

This paper characterizes a sheep model of chondroitinase-induced intervertebral disc degeneration to evaluate biomaterials for disc repair.

bioRxiv · May 25, 2020Bioengineering

Differential Effector Response of Amnion- and Adipose-Derived Mesenchymal Stem Cells to Inflammation; Implications for Intradiscal Therapy

R. Borem, A. Madeline, M. Bowman, S. Gill, J. Tokish, J. Mercuri

This study compares the inflammatory response of amnion- and adipose-derived mesenchymal stem cells in intervertebral disc degeneration, finding AM-MSCs produce more anti-inflammatory cytokines and chondrogenic matrix while AD-MSCs proliferate more and produce pro-inflammatory cytokines.

bioRxiv · Jan 17, 2019Bioengineering

Multi-laminate Annulus Fibrosus Repair Scaffold with an Interlamellar Matrix Enhances Impact Resistance, Prevents Herniation and Assists in Restoring Spinal Kinematics

R. Borem, A. Madeline, R. Vela, S. Gill, J. Mercuri

This study enhances a collagen-based scaffold with a glycosaminoglycan interlamellar matrix to improve impact resistance, restore spinal kinematics, and prevent disc herniation.

bioRxiv · Sep 14, 2018Bioengineering

A pilot investigation of chemonucleolysis-induced intervertebral disc degeneration in the ovine lumbar spine

R. Borem, J. Walters, A. Madeline, L. Madeline, J. Easley, S. Gill, J. Mercuri

This study investigates chemonucleolysis-induced intervertebral disc degeneration in ovine lumbar spines, showing significant biochemical, biomechanical, and histological changes resembling human IVD degeneration.

bioRxiv · Aug 3, 2018 · PreprintBioengineering