Author

J. Ungewiss

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Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Tomas· 1 shared B. Jones· 1 shared G. A. Rutter· 1 shared J. Minnion· 1 shared K. Schoeneberg· 1 shared M. Lucey· 1 shared P. Pickford· 1 shared S. R. Bloom· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Tomas

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1 paper

Recent·Most cited

Disconnect between signalling potency and in vivo efficacy of pharmacokinetically optimised biased glucagon-like peptide-1 receptor agonists

M. Lucey, P. Pickford, J. Minnion, J. Ungewiss, K. Schoeneberg, G. A. Rutter, S. R. Bloom, A. Tomas, B. Jones

This study evaluates how C-terminal acylation affects GLP-1R signal bias and in vivo efficacy, finding that acylated ligands show improved therapeutic potential despite reduced potency.

bioRxiv · Nov 26, 2019Pharmacology & Toxicology