BiophysicsbioRxivPreprint
De novo design of drug-binding proteins with predictable binding energy and specificity
L. Lu, X. Gou, S. Tan…·W. DeGrado
This paper designs drug-binding proteins with low nanomolar affinity and predictable specificity using computational methods, validated by experimental measurements and structural analysis.
DOI 10.1101/2023.12.23.573178