Therapeutic role of recurrent ESR1-CCDC170 gene fusions in breast cancer endocrine resistance
L. Li, L. Lin, J. Veeraraghavan, Y. Hu, X. Wang, S. Lee, Y. Tan, R. Schiff, x. wang
This study investigates the role of ESR1-CCDC170 gene fusions in breast cancer endocrine resistance, showing they reduce endocrine sensitivity and can be targeted with HER2/SRC inhibitors.
bioRxiv · Jun 26, 2020Cancer Biology