Targeted Protein O-GlcNAcylation Using Bifunctional Small Molecules
B. Ma, K. S. Khan, T. Xu, J. X. Amada, Z. Guo, Y. Yan, A. S.-L. Cheng, B. W.-L. Ng
This paper develops OGTACs, bifunctional small molecules that enable protein-specific O-GlcNAcylation in cells, with applications for studying and targeting this modification in disease.
bioRxiv · Jun 9, 2023Cell Biology