Diverse Hotspot Thermal Profiling Methods Detect Phosphorylation-Dependent Changes in Protein Stability
B. D. Stein, J. X. Huang, D. Wu, L. C. Cantley, R. E. Moellering
The paper compares two HTP methods, finding that LFE-HTP improves proteoform coverage and detects novel phosphorylation sites affecting protein stability.
bioRxiv · May 1, 2021 · PreprintBiochemistry