Inhibition of the Receptor for Advanced Glycation End-Products in Acute Respiratory Distress Syndrome: A Randomised Laboratory Trial in Piglets
J. Audard, T. Godet, R. Blondonnet, J.-B. Joffredo, B. Paquette, C. Belville, M. Lavergne, C. Gross, J. Pasteur, D. Bouvier, L. Blanchon, V. Sapin, B. Pereira, J.-M. Constantin, M. Jabaudon
This study tests RAGE inhibition in a piglet model of ARDS, finding improved alveolar fluid clearance and reduced lung injury with RAP or sRAGE treatment.
bioRxiv · Aug 31, 2018Physiology