B. Pereira

A new genome-scale metabolic model of oleaginous microalgae with refined lipid metabolism elucidates Microchloropsis gaditana mutant phenotypes.

This paper presents a genome-scale metabolic model for Microchloropsis gaditana that captures lipid metabolism and mutant phenotypes, enhancing understanding of its metabolic capabilities.

Internal Translation of p53 Oncoproteins During Integrated Stress Response Confers Survival Advantage on Cancer Cells

This study identifies the integrated stress response (ISR) as a trigger for p53 oncoprotein variants, showing their role in cancer cell survival and proposing a therapeutic strategy.

A cell state specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma

The paper identifies a metabolic vulnerability in specific glioma cell states that can be targeted with GPX4 inhibitors to induce ferroptosis.

TLR4 regulation in human fetal membranes as an explicative mechanism of a pathological preterm case.

This study identifies dual epigenetic and miRNA regulatory mechanisms controlling TLR4 expression in human fetal membranes, linking them to sterile inflammation and preterm rupture.

Single-cell analysis reveals diverse stromal subsets associated with immune evasion in triple-negative breast cancer

This study identifies diverse stromal subsets in TNBC using single-cell RNA-seq and links them to immune evasion mechanisms and therapeutic targets.

Inhibition of the Receptor for Advanced Glycation End-Products in Acute Respiratory Distress Syndrome: A Randomised Laboratory Trial in Piglets

This study tests RAGE inhibition in a piglet model of ARDS, finding improved alveolar fluid clearance and reduced lung injury with RAP or sRAGE treatment.