J.-C. Galas

Long-lasting and responsive DNA/enzyme-based programs in serum-supplemented extracellular media

This paper demonstrates DNA/enzyme programs functional in serum for 3 days, with a new buffer enhancing biocompatibility and responsiveness, and shows their sustainability in the presence of living cells.

DNA-controlled Spatio-temporal Patterning of a Cytoskeletal Active Gel

This study demonstrates DNA-controlled spatio-temporal patterning of a cytoskeletal active gel by triggering molecular motor release, leading to periodic band patterns or global contraction.

Programmed mechano-chemical coupling in reaction-diffusion active matter

This study couples reaction-diffusion and active matter mechanisms in synthetic materials to mimic mechano-chemical processes in C. elegans oocytes.

Spatio-temporal patterning of living cells withextracellular DNA programs

The paper demonstrates that synthetic extracellular DNA programs can control spatio-temporal cell internalization by leveraging non-equilibrium dynamics and reaction-diffusion patterns.

DNA-based long-lived reaction-diffusion patterning in a host hydrogel

This paper demonstrates DNA/enzyme reaction-diffusion patterns in hydrogels that are long-lived and autonomous, mimicking living matter's properties.

rEXPAR: an isothermal amplification scheme that is robust to autocatalytic parasites

The paper introduces rEXPAR, a modified EXPAR method that prevents parasite formation by altering template design and removing dATP, while maintaining compatibility with PEN DNA toolbox programs.