NeurosciencebioRxivPreprint
Excitatory neuron-specific suppression of the integrated stress response pathway contributes to autism-related phenotypes in a mouse model of fragile X syndrome
M. Hooshmandi, V. Sharma, C. T. Perez…·A. Khoutorsky
The paper shows that suppressing the ISR pathway in excitatory neurons of FXS mice leads to autism-like behaviors and that restoring it rescues these phenotypes.
DOI 10.1101/2023.04.24.538123