GCN5 Maintains Muscle Integrity by Acetylating YY1 to Promote Dystrophin Expression
G. C. Addicks, H. Zhang, D. Ryu, G. Vasam, P. L. Marshall, A. E. Green, S. Patel, B. E. Kang, D. Kim, E. Katsyuba, E. G. Williams, J.-M. Renaud, J. Auwerx, K. J. Menzies
This study shows GCN5 acetylates YY1, reducing its DNA binding and increasing dystrophin expression, which maintains muscle integrity in mice.
bioRxiv · Mar 29, 2021Cell Biology