Addressing the Most Neglected Diseases through an Open Research Model: the Discovery of Fenarimols as Novel Drug Candidates for Eumycetoma
W. Lim, Y. Melse, M. Konings, H. P. Duong, K. Eadie, B. Laleu, B. Perry, M. Todd, J.-R. Ioset, W. van de Sande
This paper identifies new drug candidates for eumycetoma by screening 800 compounds and testing their in vitro and in vivo activity against Madurella mycetomatis, using an open-source approach to accelerate drug discovery.
bioRxiv · Feb 2, 2018Pharmacology & Toxicology