HDGF supports anti-apoptosis and pro-fibrosis in pancreatic stellate cells of pancreatic cancer
Y.-T. Chen, T.-W. Wang, T.-H. Chang, T.-P. Hsu, J.-Y. Chi, Y.-W. Hsiao, C.-F. Li, J.-M. Wang
This study identifies the TGF-β1-activated CEBPD/HIF-1/HDGF axis in pancreatic stellate cells, showing HDGF promotes anti-apoptosis and pro-fibrosis, contributing to pancreatic cancer progression.
bioRxiv · Nov 6, 2018 · PreprintCancer Biology