Author

Y.-W. Hsiao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

C.-F. Li· 1 shared D. J. Bray· 1 shared G. Jimenez-Serratos· 1 shared J. Crain· 1 shared J.-M. Wang· 1 shared J.-Y. Chi· 1 shared T. Taddese· 1 shared T.-H. Chang· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

C.-F. Li

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Structure adaptation in Omicron SARS-CoV-2/hACE2:Biophysical origins of evolutionary driving forces

Y.-W. Hsiao, T. Taddese, G. Jimenez-Serratos, D. J. Bray, J. Crain

This study uses molecular dynamics simulations to analyze structural and electrostatic changes in the SARS-CoV-2 Omicron variants (BA.1 and BA.2) compared to the wild type, revealing how mutations affect spike protein-hACE2 interactions and binding mechanisms.

bioRxiv · Dec 20, 2022Biophysics

HDGF supports anti-apoptosis and pro-fibrosis in pancreatic stellate cells of pancreatic cancer

Y.-T. Chen, T.-W. Wang, T.-H. Chang, T.-P. Hsu, J.-Y. Chi, Y.-W. Hsiao, C.-F. Li, J.-M. Wang

This study identifies the TGF-β1-activated CEBPD/HIF-1/HDGF axis in pancreatic stellate cells, showing HDGF promotes anti-apoptosis and pro-fibrosis, contributing to pancreatic cancer progression.

bioRxiv · Nov 6, 2018 · PreprintCancer Biology