The modular evolution of chitinases is governed by coevolution of auxiliary and catalytic domains
Sacha B. Pulsford, Jack A. T. Dalton, Oliver B. Smith, Jack Horton, Rebecca L. Frkic, John Z. Chen, Joe A. Kaczmarski, Colin J. Jackson
This study maps the sequence space of bacterial chitinases to show how domain composition and catalytic core evolve differently based on functional roles.
bioRxiv · Jan 16, 2026 · PreprintEvolutionary Biology