Intranasal administration of isradipine preferentially targets the brain
Jaime N. Guzmán, Ema IIijic, Jack T Nguyen, Dalton James Surmeier
This study shows that intranasal administration of isradipine achieves higher brain concentrations than plasma, enabling targeted Cav1 Ca2+ channel inhibition with fewer peripheral side effects.
bioRxiv · Mar 10, 2025 · PreprintNeuroscience