Histone H3 dopaminylation in ventral tegmental area underlies heroin-induced maladaptive plasticity
Sasha L. Fulton, Swarup Mitra, Ashley E. Lepack, Jennifer A. Martin, Andrew Francis Stewart, Jacob Converse, Mason J. Hochstetler, David Dietz, Ian S. Maze
This study shows that H3Q5dop in VTA contributes to heroin-induced transcriptional plasticity and relapse vulnerability during abstinence.
Neuropsychopharmacology · Jan 29, 2022Peer-reviewedNeuroscience