Cancer BiologybioRxivPreprint
Patient-derived organoids reveal hypoxia-driven plasticity and therapeutic vulnerabilities in pheochromocytomas and paragangliomas
Xiaojing Wang, Maite Calucho, Cynthia M. Estrada-Zuniga…·Patricia L. M. Dahia
This study uses patient-derived organoids to model pheochromocytomas and paragangliomas, revealing hypoxia-driven plasticity and therapeutic vulnerabilities, including responses to abemaciclib.
DOI 10.1101/2025.08.22.671868